Endocrine Abstracts

Objectives: GHR in adults with GHD favourably effects body composition (reduces fat and increases lean body mass) although body weight usually remains unchanged. However the effect of GHR on ingestive behaviour and voluntary physical activity in adults has not been studied.Methods: We studied 10 hypopituitary adults (8 males, 2 females, mean age 49.7 years) with severe GHD (mean peak GH response to glucagon 3.26 mU/l, baseline IGF-1 level 14.5 nmol/L) be...